
Synthetic Biology quiz
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Why is cell-free protein synthesis ideal for producing toxic therapeutic proteins?
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More questions about Synthetic Biology
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Which four bases are used to encode binary data in synthetic DNA storage?
Answer: Adenine, cytosine, guanine, thymine
Why: A 2017 Science team wrote an operating system and a film into DNA and hit 215 petabytes per gram, all in A, C, G and T.
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What is the purpose of adding a degradation tag to a synthetic protein?
Answer: Controlling its cellular lifetime
Why: Bacteria's own ssrA tag does the job: its last three amino acids swing a tagged protein's half-life from 40 minutes to 110.
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Why are synthetic yeast chromosomes designed without repetitive DNA sequences?
Answer: To prevent recombination
Why: Sc2.0 went further: all 275 tRNA genes moved to a new 17th chromosome, because busy tRNA genes stall replication forks.
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What targets do bacteria naturally use CRISPR systems to destroy?
Answer: Viruses
Why: Proof came from yogurt in 2007: dairy bacteria hit by phages filed scraps of the viral DNA into their CRISPR array and survived the next attack.
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What causes genetic drift in synthetic bacteria over many generations?
Answer: Random mutation accumulation
Why: Mutations are only the start: a broken circuit costs less energy, so mutant cells outgrow the engineered ones, sometimes within 20 generations.
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Which codon is most often repurposed to encode non-canonical amino acids?
Answer: Amber stop codon
Why: E. coli carries just 321 amber stop codons, and in 2013 a team swapped every one for UAA, freeing UAG as a blank slot for synthetic amino acids.